Mycobacterium tuberculosis infection of domesticated Asian elephants, Thailand.
نویسندگان
چکیده
Alexander Rosewell, Rosheila Dagina, Manoj Murhekar, Berry Ropa, Enoch Posanai, Samir Dutta, Ian Barr, Glen Mola, Anthony Zwi, and C. Raina MacIntyre Author affi liations: World Health Organization, Port Moresby, Papua New Guinea (A. Rosewell, M. Murhekar); University of New South Wales, Sydney, New South Wales, Australia (A. Rosewell, A. Zwi, C.R. MacIntyre); National Department of Health, Port Moresby (R. Dagina, B. Ropa, E. Posanai); Port Moresby General Hospital, Port Moresby (S. Dutta); World Health Organization Collaborating Center for Reference and Research on Infl uenza, Melbourne, Victoria, Australia (I. Barr); and University of Papua New Guinea, Port Moresby (G. Mola)
منابع مشابه
Mycobacterium tuberculosis Infection of Domesticated Asian Elephants, Thailand
Four Asian elephants were confirmed to be infected with Mycobacterium tuberculosis by bacterial culture, other diagnostic procedures, and sequencing of 16S-23S rDNA internal transcribed spacer region, 16S rRNA, and gyrase B gene sequences. Genotyping showed that the infectious agents originated from 4 sources in Thailand. To identify infections, a combination of diagnostic assays is essential.
متن کاملMycobacterium tuberculosis in Wild Asian Elephants, Southern India
We tested 3 ild Asian elephants (Elephas maximus) in southern India and confirmed infection in 3 animals with Mycobacterium tuberculosis, an obligate human pathogen, by PCR and genetic sequencing. Our results indicate that tuberculosis may be spilling over from humans (reverse zoonosis) and emerging in wild elephants.
متن کاملMycobacterium tuberculosis Infection among Asian Elephants in Captivity
Although awareness of tuberculosis among captive elephants is increasing, antituberculosis therapy for these animals is not standardized. We describe Mycobacterium tuberculosis transmission between captive elephants based on whole genome analysis and report a successful combination treatment. Infection control protocols and careful monitoring of treatment of captive elephants with tuberculosis ...
متن کاملMycobacterium tuberculosis Infection in Free-Roaming Wild Asian Elephant
Postmortem examination of a wild Asian elephant at Rajiv Gandhi National Park, India, revealed nodular lesions, granulomas with central caseation, and acid-fast bacilli in the lungs. PCR and nucleotide sequencing confirmed the presence of Mycobacterium tuberculosis. This study indicates that wild elephants can harbor M. tuberculosis that can become fatal.
متن کاملEvaluation of a multiple-antigen enzyme-linked immunosorbent assay for detection of Mycobacterium tuberculosis infection in captive elephants.
Mycobacterium tuberculosis has become an important agent of disease in the captive elephant population of the United States, although current detection methods appear to be inadequate for effective disease management. This investigation sought to validate a multiple-antigen enzyme-linked immunosorbent assay (ELISA) for screening of M. tuberculosis infection in captive elephants and to document ...
متن کامل